Panama City (PTY) → Mexico City (MEX)

2,411 km
3h 31m flight
From $380
Mexico City destination photo

About Panama City to Mexico City Flights

Discover the best flights from Panama City to Mexico City, covering 2,411 km in approximately 3h 31m. Panama City (PTY) to Mexico City (MEX) is one of the popular medium-haul routes connecting Panama and Mexico. With 7 major airlines operating this route including direct flights, travelers have plenty of options to choose from. Whether you're traveling for business or leisure, our comprehensive guide helps you find the best deals, understand seasonal price variations, and choose the right airline for your journey from Panama City to Mexico City.

12-Month Price History

Flight prices from Panama City to Mexico City vary significantly throughout the year. February typically offers the best deals with average prices around $508, while July sees the highest prices, averaging $852. Savvy travelers can save up to 40% by choosing their travel dates wisely.

Best Time to Fly

Cheapest Month

February

Save up to 40% on average

Most Expensive

July

Peak season pricing

Book in Advance

177 days

For best prices

Booking Tips

For the best prices on Panama City to Mexico City flights, we recommend booking 63 days in advance. International flights typically see price increases as the departure date approaches, so early booking is advisable. Tuesday and Wednesday departures often offer the lowest fares, while Friday and Sunday flights tend to be more expensive due to business and leisure travel demand. Consider flying early morning or late evening for additional savings, as these off-peak times usually have lower demand.

Airlines Serving This Route

Interjet

4O

Economy

$780

Business

$3260

First

$4760

Aeroméxico

AM

Economy

$830

Business

$3190

First

$4360

Delta Air Lines

DL

Economy

$880

Business

$3140

First

$5640

Copa Airlines

CM

Economy

$950

Business

$2830

First

$4390

American Airlines

AA

Economy

$960

Business

$3180

First

$4970

Copa Airlines

CM

Economy

$970

Business

$2770

First

$4840

Volaris

Y4

Economy

$980

Business

$3510

First

$5600

Prices shown are estimates based on historical data. Actual prices may vary based on dates, availability, and current promotions.

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Frequently Asked Questions

How long is the flight from Panama City to Mexico City?

The flight time from Panama City (PTY) to Mexico City (MEX) is approximately 3 hours and 31 minutes. This duration is for direct flights and may vary depending on aircraft type, weather conditions, and air traffic.

What is the distance between Panama City and Mexico City?

The aerial distance between Panama City and Mexico City is 2,411 kilometers (1,498 miles). This is the straight-line distance, which is used to calculate flight times.

Which airlines fly from Panama City to Mexico City?

Several airlines operate flights between Panama City and Mexico City, including Aeroméxico, Copa Airlines, Volaris and 4 more airlines. Direct flights are available on this route.

What is the cheapest month to fly from Panama City to Mexico City?

Based on historical data, February typically offers the lowest airfares for flights from Panama City to Mexico City. However, prices can vary based on holidays, events, and airline promotions. We recommend checking our price calendar for the most up-to-date information.

How far in advance should I book my flight to Mexico City?

For the best prices on Panama City to Mexico City flights, we recommend booking 135 days in advance. International flights generally require earlier booking than domestic routes.

Do I need a visa to travel from Panama City to Mexico City?

Visa requirements depend on your nationality and the purpose of your visit. Citizens of Panama traveling to Mexico should check the latest visa requirements. Visit our partner site visarequirements.io for detailed visa information.

What is the time difference between Panama City and Mexico City?

Panama City operates on America/Panama time zone, while Mexico City is in the America/Mexico_City time zone. For current time differences and to plan your schedule, visit our partner site timezig.com for accurate timezone conversions.